Recommendations for drug therapy of heart failure
Clinical inclusion & exclusion criteria
LVEF < 40% with or without symptoms
Dyslipidemia
Coronary artery disease
Bradyarrhythmia
NYHA I
Carotid sinus syndrome
NYHA II-III
AV-Block II / III°
NYHA III-IV
Tachycard atrial fibrillation
QRS > 150ms
QRS 120-150ms
QRS < 120ms
Hypertrophic obstructive Cardiomyopathy
Diastolic dysfunction
Renal failure (creatinine clearance < 30ml/min)
Arterial hypertension
Hyperkalemia (K > 6.0mmol/l)
Asthma
Hypokalemia (K < 3.5mmol/l)
COPD
Bilateral renal artery stenosis
Diabetes mellitus / impaired glucose tolerance
Angioedema
Proteinuria, Microalbuminuria
Gout
Diabetic nephropathy
Pregnancy
Lactation
β-Blockers
highly cardio selective
cardio selective or non selective with ISA
ACE-inhibitors
AT-II receptor antagonists
Diuretics (primarily loop diuretics)
Aldosteron antagonists
Digoxin
Cardiac Resynchronization Therapy (CRT)